The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2012

Filed:

Nov. 30, 2007
Applicants:

Caterina Bissantz, Village Neuf, FR;

Christophe Grundschober, Rodersdorf, CH;

Raffaello Masciadri, Basel, CH;

Hasane Ratni, Habsheim, FR;

Mark Rogers-evans, Oberwil, CH;

Patrick Schnider, Bottmingen, CH;

Inventors:

Caterina Bissantz, Village Neuf, FR;

Christophe Grundschober, Rodersdorf, CH;

Raffaello Masciadri, Basel, CH;

Hasane Ratni, Habsheim, FR;

Mark Rogers-Evans, Oberwil, CH;

Patrick Schnider, Bottmingen, CH;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 31/438 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with novel indol-2-yl-carbonyl-spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use for the treatment of anxiety, depressive disorders and other diseases. The compounds of present invention are represented by the general formula (I) wherein Rto R, X and Y are as defined in the specification.


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