The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2012
Filed:
Feb. 10, 2010
Applicants:
Tao Lan, Arlington, MA (US);
Ekambar Kandimalla, Southboro, MA (US);
Daqing Wang, Bedford, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Inventors:
Tao Lan, Arlington, MA (US);
Ekambar Kandimalla, Southboro, MA (US);
Daqing Wang, Bedford, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Assignee:
Idera Pharmaceuticals, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); A61K 49/00 (2006.01); A61K 31/70 (2006.01); A01N 43/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA-based oligoribonucleotides with improved nuclease and RNase stability and that selectively induce immune modulatory activity through TLR7.