The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2012

Filed:

Nov. 13, 2008
Applicants:

Shaomeng Wang, Saline, MI (US);

Haiying Sun, Ann Arbor, MI (US);

Dongguang Qin, Ann Arbor, MI (US);

Zaneta Nikolovska-coleska, Ann Arbor, MI (US);

Jianfeng LU, Ann Arbor, MI (US);

Su Qiu, Ann Arbor, MI (US);

Yuefeng Peng, Ann Arbor, MI (US);

Qian Cai, Ann Arbor, MI (US);

Inventors:

Shaomeng Wang, Saline, MI (US);

Haiying Sun, Ann Arbor, MI (US);

Dongguang Qin, Ann Arbor, MI (US);

Zaneta Nikolovska-Coleska, Ann Arbor, MI (US);

Jianfeng Lu, Ann Arbor, MI (US);

Su Qiu, Ann Arbor, MI (US);

Yuefeng Peng, Ann Arbor, MI (US);

Qian Cai, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 47/10 (2006.01); A61K 31/27 (2006.01); C07D 225/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.


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