The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2012
Filed:
Mar. 12, 2009
Applicants:
Gary D. Lopaschuk, Edmonton, CA;
John C. Vederas, Edmonton, CA;
Jason R. Dyck, Sherwood Park, CA;
Inventors:
Assignee:
The Governors of the University of Alberta, Edmonton, Alberta, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/02 (2006.01); C07C 69/74 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R, R, R, R, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.