The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2012

Filed:

Sep. 24, 2007
Applicants:

Pamela Albaugh, Carlsbad, CA (US);

Gregory B. Chopiuk, San Diego, CA (US);

Qiang Ding, San Diego, CA (US);

Shenlin Huang, San Diego, CA (US);

Zuosheng Liu, San Diego, CA (US);

Shifeng Pan, San Diego, CA (US);

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Xing Wang, San Diego, CA (US);

Yongping Xie, San Diego, CA (US);

Chengzhi Zhang, San Diego, CA (US);

Qiong Zhang, Union City, CA (US);

Guobao Zhang, San Diego, CA (US);

Daniel Poon, Oakland, CA (US);

Paul Renhowe, Danville, CA (US);

Martin Sendzik, San Mateo, CA (US);

Inventors:

Pamela Albaugh, Carlsbad, CA (US);

Gregory B. Chopiuk, San Diego, CA (US);

Qiang Ding, San Diego, CA (US);

Shenlin Huang, San Diego, CA (US);

Zuosheng Liu, San Diego, CA (US);

Shifeng Pan, San Diego, CA (US);

Pingda Ren, San Diego, CA (US);

Xia Wang, San Diego, CA (US);

Xing Wang, San Diego, CA (US);

Yongping Xie, San Diego, CA (US);

Chengzhi Zhang, San Diego, CA (US);

Qiong Zhang, Union City, CA (US);

Guobao Zhang, San Diego, CA (US);

Daniel Poon, Oakland, CA (US);

Paul Renhowe, Danville, CA (US);

Martin Sendzik, San Mateo, CA (US);

Assignees:

IRM LLC, Hamilton, BM;

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); C07D 417/00 (2006.01); C07D 419/00 (2006.01); C07D 231/00 (2006.01); C07D 403/02 (2006.01); A01N 43/56 (2006.01); A61K 31/415 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.


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