The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2012
Filed:
Dec. 01, 2010
Sudhir Agrawal, Shrewsbury, MA (US);
Ekambar R. Kandimalla, Southboro, MA (US);
Dong Yu, Westboro, MA (US);
Lakshmi Bhagat, Brookline, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Ekambar R. Kandimalla, Southboro, MA (US);
Dong Yu, Westboro, MA (US);
Lakshmi Bhagat, Brookline, MA (US);
Idera Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The invention relates to the therapeutic use of oligonucleotides as immunostimulatory agents in immunotherapy applications. More particularly, the invention provides immunomers for use in methods for generating an immune response or for treating a patient in need of immunostimulation. The immunomers of the invention comprise at least two oligonucleotides linked at their 3' ends, internucleoside linkages or functionalized nucleobase or sugar to a non-nucleotidic linker, at least one of the oligonucleotides being an immunostimulatory oligonucleotide and having an accessible 5′ end.