The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 19, 2012

Filed:

Oct. 03, 2008
Applicants:

Bernard Luke Flynn, Vermont, AU;

Jonathan Bayldon Baell, Ivanhoe, AU;

Jason Hugh Chaplin, DoubleView, AU;

Gurmit Singh Gill, Craigieburn, AU;

Damian Wojciech Grobelny, Watsonia, AU;

Andrew John Harvey, Goodwood, AU;

Jorgen Alvar Mould, Semaphore, AU;

Dharam Paul, Torrensville, AU;

Inventors:

Bernard Luke Flynn, Vermont, AU;

Jonathan Bayldon Baell, Ivanhoe, AU;

Jason Hugh Chaplin, DoubleView, AU;

Gurmit Singh Gill, Craigieburn, AU;

Damian Wojciech Grobelny, Watsonia, AU;

Andrew John Harvey, Goodwood, AU;

Jorgen Alvar Mould, Semaphore, AU;

Dharam Paul, Torrensville, AU;

Assignee:

Bionomics Limited, Thebarton, South Australia, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/21 (2006.01); A61K 31/138 (2006.01); A61K 31/4402 (2006.01); A61K 31/5375 (2006.01); A61K 31/4453 (2006.01); A61K 31/40 (2006.01); A61K 31/4965 (2006.01); A61K 31/54 (2006.01); A61K 31/4174 (2006.01); A61K 31/4196 (2006.01); A61K 31/397 (2006.01); A61K 31/198 (2006.01); A61K 39/395 (2006.01); C07C 215/64 (2006.01); A61P 29/00 (2006.01); A61P 3/10 (2006.01); A61P 25/28 (2006.01); C07D 213/54 (2006.01); C07D 265/30 (2006.01); C07D 211/34 (2006.01); C07D 211/74 (2006.01); C07D 207/08 (2006.01); C07D 241/18 (2006.01); C07D 279/12 (2006.01); C07D 233/60 (2006.01); C07D 249/08 (2006.01); C07D 205/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.


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