The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
May. 20, 2011
Ulrich Abel, Heidelberg, DE;
Holger Deppe, Heidelberg, DE;
Achim Feurer, Auggen, DE;
Ulrich Grädler, Heidelberg, DE;
Kerstin Otte, Heidelberg, DE;
Renate Sekul, Ladenburg, DE;
Meinolf Thiemann, Schriesheim, DE;
Andreas Goutopoulos, Boston, MA (US);
Matthias Schwarz, Glard, CH;
Xuliang Jiang, Braintree, MA (US);
Ulrich Abel, Heidelberg, DE;
Holger Deppe, Heidelberg, DE;
Achim Feurer, Auggen, DE;
Ulrich Grädler, Heidelberg, DE;
Kerstin Otte, Heidelberg, DE;
Renate Sekul, Ladenburg, DE;
Meinolf Thiemann, Schriesheim, DE;
Andreas Goutopoulos, Boston, MA (US);
Matthias Schwarz, Glard, CH;
Xuliang Jiang, Braintree, MA (US);
Merck Serono S.A., Coinsins, Vaud, CH;
Abstract
The invention provides novel, substituted 3-arylamino pyridine compounds pharmaceutically acceptable salts, solvates and prodrug compounds thereof, wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Also disclosed is the use of such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and pharmaceutical compositions containing such compounds.