The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
Jan. 07, 2008
Werner Bonrath, Freiburg, DE;
Ralph Haerter, Biel-Benken, CH;
Reinhard Karge, Staufen, DE;
Ulla Letinois, Saint-Louis, FR;
Werner Bonrath, Freiburg, DE;
Ralph Haerter, Biel-Benken, CH;
Reinhard Karge, Staufen, DE;
Ulla Letinois, Saint-Louis, FR;
DSM IP Assets B.V., Heerlen, NL;
Abstract
Process for the manufacture of a compound of the structure (I) with R=hydrogen, alkyl (C1-C10, linear, cyclic or branched, aliphatic or aromatic), NR'R″ (wherein R′ and R″ are independently selected from H, alkyl [C1-C10, linear, cyclic or branched, aliphatic or aromatic] and R=CHRwherein Ris selected from NHR1′″ (with R′″=C(O)H, C(O)CH, C(O)alkyl, CHCH(OMe)or other saponifiable residues), alkyl (C1-C10, linear, cyclic or branched) aromatic residues, heteroaryl residues, substituted aryl residues, e.g. 3,4,5-trimethoxy-phenyl) wherein 1 equivalent of an α-formyl-propionitrile salt is reacted with 0.75 to 2 equivalents of an acetamidine salt in the presence of a Lewis acid.