The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Apr. 12, 2010
Applicants:

Kuo-hsiung Lee, Chapel Hill, NC (US);

LI Lin, Chapel Hill, NC (US);

Charles C-y Shih, Solana Beach, CA (US);

Ching-yuan Su, San Diego, CA (US);

Junko Ishida, Tokyo, JP;

Hironori Ohtsu, Matsubara, JP;

Hui-kang Wang, San Diego, CA (US);

Hideji Itokawa, Chapel Hill, NC (US);

Chawnshang Chang, Pittsford, NY (US);

Inventors:

Kuo-Hsiung Lee, Chapel Hill, NC (US);

Li Lin, Chapel Hill, NC (US);

Charles C-Y Shih, Solana Beach, CA (US);

Ching-Yuan Su, San Diego, CA (US);

Junko Ishida, Tokyo, JP;

Hironori Ohtsu, Matsubara, JP;

Hui-Kang Wang, San Diego, CA (US);

Hideji Itokawa, Chapel Hill, NC (US);

Chawnshang Chang, Pittsford, NY (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/235 (2006.01); C12N 5/00 (2006.01); C07C 49/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.


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