The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Jun. 18, 2009
Applicants:

Aude Fayol, Paris, FR;

Thierry Gallet, Paris, FR;

Alistair Lochead, Paris, FR;

Mourad Saady, Paris, FR;

Corinne Veronique, Paris, FR;

Philippe Yaiche, Paris, FR;

Inventors:

Aude Fayol, Paris, FR;

Thierry Gallet, Paris, FR;

Alistair Lochead, Paris, FR;

Mourad Saady, Paris, FR;

Corinne Veronique, Paris, FR;

Philippe Yaiche, Paris, FR;

Assignees:

Sanofi-Aventis, Paris, FR;

Tanabe Pharma Corporation, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 239/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof are disclosed and claimed. Wherein m, n, o, Y, Z, R1, R2, R3, R4, R5 R6 and R7 are as described herein. Also disclosed are the salts of compounds of formula (I). The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.


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