The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
Sep. 28, 2009
Takafumi Motoki, Tsukuba, JP;
Kunitoshi Takeda, Tsukuba, JP;
Yoichi Kita, Tsukuba, JP;
Mamoru Takaishi, Tsukuba, JP;
Yuichi Suzuki, Tsukuba, JP;
Tasuku Ishida, Tsukuba, JP;
Takafumi Motoki, Tsukuba, JP;
Kunitoshi Takeda, Tsukuba, JP;
Yoichi Kita, Tsukuba, JP;
Mamoru Takaishi, Tsukuba, JP;
Yuichi Suzuki, Tsukuba, JP;
Tasuku Ishida, Tsukuba, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
A compound represented by the general formula: wherein Ring A is a Caryl group or the like, L is —NRCO— or the like (wherein Ris a hydrogen atom or the like), Ring B is a Caryl group or the like, X is a Calkylene group or the like, Y is a Calkylene group or the like, Z is an oxygen atom or the like, Rand Rare each independently a hydrogen atom or the like, and R, R, Rand Rare independently a hydrogen atom, a halogen atom or the like, or a pharmaceutically acceptable salt thereof, or a solvate thereof, has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.