The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
Mar. 26, 2009
Zhi HU, El Cerrito, CA (US);
Wen-lin Kuo, San Ramon, CA (US);
Richard M. Neve, San Mateo, CA (US);
Joe W. Gray, San Francisco, CA (US);
Zhi Hu, El Cerrito, CA (US);
Wen-Lin Kuo, San Ramon, CA (US);
Richard M. Neve, San Mateo, CA (US);
Joe W. Gray, San Francisco, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Amplification of the ANXA9 gene in human chromosomal region 1q21 in epithelial cancers indicates a likelihood of both in vivo drug resistance and metastasis, and serves as a biomarker indicating these aspects of the disease. ANXA9 can also serve as a therapeutic target. Interfering RNAs (iRNAs) (such as siRNA and miRNA) and shRNA adapted to inhibit ANXA9 expression, when formulated in a therapeutic composition, and delivered to cells of the tumor, function to treat the epithelial cancer.