The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Mar. 06, 2007
Applicants:

Zoltan Kovacs, Lewisville, TX (US);

Garry E. Kiefer, Richardson, TX (US);

Corinne Bensimon, Nepean, CA;

A. Dean Sherry, Dallas, TX (US);

Gyula Tircso, Debrecen, HU;

Inventors:

Zoltan Kovacs, Lewisville, TX (US);

Garry E. Kiefer, Richardson, TX (US);

Corinne Bensimon, Nepean, CA;

A. Dean Sherry, Dallas, TX (US);

Gyula Tircso, Debrecen, HU;

Assignee:

Nordion (Canada) Inc., Kanata, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/532 (2006.01); C07D 257/00 (2006.01); C07D 273/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A bifunctional polyazamacrocyclic chelating agent of the formula (I): wherein: and the variables A, L, Q, Q, X, Y, Z, Z, m, n and r are as defined in the description of the present application. Also described is a complex of the above chelating agent to an ion of a metal ion, such as an ion ofY,Li orLu; a conjugate of the complex covalently attached to a biological carrier; and a pharmaceutical composition containing the conjugate. A method of therapeutic treatment of a mammal involving administration of the pharmaceutical composition is also described.


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