The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Apr. 03, 2003
Applicants:

Tatyana A. Zhukov, Lutz, FL (US);

Melvyn S. Tockman, Tampa, FL (US);

Roy A. Johanson, Bryn Mawr, PA (US);

Inventors:

Tatyana A. Zhukov, Lutz, FL (US);

Melvyn S. Tockman, Tampa, FL (US);

Roy A. Johanson, Bryn Mawr, PA (US);

Assignees:

University of South Florida, Tampa, FL (US);

Ciphergen Biosystems, Inc., Fremont, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is a method for early detection of cancer including the steps of identifying tissue from asymptomatic individuals, gathering a substantially homogenous cell population from the tissue by laser capture microdissection (LCM), analyzing the cell population with mass spectrometry and identifying predetermined peaks in the mass spectrometry associated with an overexpression of proteins in premalignant and malignant cells.


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