The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
Apr. 26, 2010
Xiaoxi (Kevin) Chen, Westborough, MA (US);
Kristina Parry, Rotherham, GB;
Anita Mistry, Sheffield, GB;
Deepa Saxena, Framingham, MA (US);
Xiaoxi (Kevin) Chen, Westborough, MA (US);
Kristina Parry, Rotherham, GB;
Anita Mistry, Sheffield, GB;
Deepa Saxena, Framingham, MA (US);
Becton, Dickinson and Company, Franklin lakes, NJ (US);
Abstract
The present invention discloses methods for producing synthetic surfaces that mimic collagen coated surfaces for cell culture comprising: providing a monomer source comprising one or more organic compounds which are capable of polymerization, wherein at least one organic compound is prolinol; creating a plasma of said monomer source; and contacting at least a portion of a surface with the plasma to provide a plasma polymer coated surface. Advantageously, such methods provide a synthetic, chemically defined surface that mimics a collagen coated surface for cell culture. Advantageously, such methods not only reduce the cost and/or issues associated with animal-derived collagen but are also amenable to large scale manufacturing.