The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 12, 2012
Filed:
Jun. 08, 2005
Indresh K. Srivastava, Benicia, CA (US);
Victoria Sharma, Orinda, CA (US);
Susan W. Barnett, San Francisco, CA (US);
Jeffrey Ulmer, Danville, CA (US);
Indresh K. Srivastava, Benicia, CA (US);
Victoria Sharma, Orinda, CA (US);
Susan W. Barnett, San Francisco, CA (US);
Jeffrey Ulmer, Danville, CA (US);
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Abstract
Provided herein are small molecule CDmimetics effective to bind to HIV Env proteins. A CDmimetic of the invention, when bound to an Env protein, is effective to induce a conformational change in the Env protein such that cyptic epitopes on the Env protein are exposed. Also provided herein are related methods of identifying and using such small molecule CDmimetics, for example, to elicit an immune response in a subject upon administration.