The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 12, 2012

Filed:

Apr. 13, 2011
Applicants:

Hiroyuki Mano, Tokyo, JP;

Sadao Kuromitsu, Tokyo, JP;

Nobuaki Shindo, Tokyo, JP;

Takatoshi Soga, Tokyo, JP;

Takashi Furutani, Tokyo, JP;

Inventors:

Hiroyuki Mano, Tokyo, JP;

Sadao Kuromitsu, Tokyo, JP;

Nobuaki Shindo, Tokyo, JP;

Takatoshi Soga, Tokyo, JP;

Takashi Furutani, Tokyo, JP;

Assignees:

Astellas Pharma Inc., Tokyo, JP;

CureGene K.K., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene.


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