The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2012

Filed:

Mar. 06, 2009
Applicants:

Yoshihisa Shinagawa, Downingtown, PA (US);

Vandana Mohan, Atlanta, GA (US);

Gerardo Hermosillo Valadez, West Chester, PA (US);

Bing Jian, Exton, PA (US);

Inventors:

Yoshihisa Shinagawa, Downingtown, PA (US);

Vandana Mohan, Atlanta, GA (US);

Gerardo Hermosillo Valadez, West Chester, PA (US);

Bing Jian, Exton, PA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for performing pharmacokinetic analysis in magnetic resonance (MR) images includes administering a dose of contrast agent (CA) into a subject. A sequence of medical images is acquired of the subject at set temporal intervals. The time-based behavior of concentrations of CA is described within the subject for each voxel of each medical image of the sequence of medical images based on a reference voxel using a compartmental model for pharmacokinetic analysis that is based on a set of compartmental model parameters. The compartmental model is solved for each of the compartmental model parameters. The solution for the compartmental model parameters is used to estimate one or more parameters of physiological significance.


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