The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2012

Filed:

Jun. 14, 2010
Applicants:

Amjad Ali, Freehold, NJ (US);

Joann Bohn, North Plainfield, NJ (US);

Qiaolin Deng, Edison, NJ (US);

Zhijian LU, Clinton, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Gayle Taylor, Red Bank, NJ (US);

Christopher Thompson, Clark, NJ (US);

Nazia Quraishi, Vienna, VA (US);

Inventors:

Amjad Ali, Freehold, NJ (US);

Joann Bohn, North Plainfield, NJ (US);

Qiaolin Deng, Edison, NJ (US);

Zhijian Lu, Clinton, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Gayle Taylor, Red Bank, NJ (US);

Christopher Thompson, Clark, NJ (US);

Nazia Quraishi, Vienna, VA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/02 (2006.01); C07D 209/04 (2006.01); C07D 307/93 (2006.01); A01N 57/26 (2006.01); A01N 57/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, Aand A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.


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