The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Sep. 15, 2006
Hashime Kanazawa, Hamura, JP;
Tomoji Aotsuka, Hamura, JP;
Kentarou Kumazawa, Hamura, JP;
Kouki Ishitani, Hamura, JP;
Takashi Nose, Hamura, JP;
Hashime Kanazawa, Hamura, JP;
Tomoji Aotsuka, Hamura, JP;
Kentarou Kumazawa, Hamura, JP;
Kouki Ishitani, Hamura, JP;
Takashi Nose, Hamura, JP;
Aska Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The compound of the present invention is a novel compound which has a specific heterocycle skeleton, particularly a pyrazolonaphthyridine or pyrazoloquinoline skeleton having an organic group (e.g., a carbocycle and a heterocycle) bonding through an alkylene group at 3-position and a carbocycle bonding at 5-position and has a phosphodiesterase IV inhibitory activity. At least one of the ring (the carbocycle or the heterocycle) bonding at 3-position of the pyrazolonaphthyridine skeleton and the carbocycle bonding at 5-position may have a halogenated alkyl group and/or a halogenated alkoxy group as a substituent. Such a compound or a salt thereof is useful as a phosphodiesterase IV inhibitor and the like. According to the present invention, a novel compound having a high phosphodiesterase IV inhibitory effect can be provided.