The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2012

Filed:

Apr. 18, 1995
Applicants:

Dan L. Eaton, San Rafael, CA (US);

Frederic J. DE Sauvage, Foster City, CA (US);

Inventors:

Dan L. Eaton, San Rafael, CA (US);

Frederic J. De Sauvage, Foster City, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/52 (2006.01); C07K 14/54 (2006.01); A61K 38/19 (2006.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

Isolated mpl ligand, isolated DNA encoding mpl ligand, and recombinant or synthetic methods of preparing mpl ligand are disclosed. These mpl ligands are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.


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