The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Nov. 16, 2007
Samuel S. Murray, Saugus, CA (US);
Elsa J. Murray, Saugus, CA (US);
Jeffrey C. Wang, Sherman Oaks, CA (US);
Keyvan Behnam, Simi Valley, CA (US);
Samuel S. Murray, Saugus, CA (US);
Elsa J. Murray, Saugus, CA (US);
Jeffrey C. Wang, Sherman Oaks, CA (US);
Keyvan Behnam, Simi Valley, CA (US);
The Regents of the University of California, Oakland, CA (US);
The United States of America as represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.