The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Mar. 08, 2007
Applicants:
Stuart Martin, Severna Park, MD (US);
Rebecca Whipple-bettes, Columbia, MD (US);
Inventors:
Stuart Martin, Severna Park, MD (US);
Rebecca Whipple-Bettes, Columbia, MD (US);
Assignee:
University of Maryland, Baltimore, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/335 (2006.01); A61K 43/16 (2006.01); A61K 31/167 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention generally concerns microtubule protrusions in cancer cells, including detached cancer cells, and inhibition of the protrusions. In particular aspects, the inhibition of the protrusions interferes with attachment of the cell to a vessel wall, and in further aspects the cell is killed by forcing it to enter capillaries and be destroyed, for example by shearing. Inhibition by a variety of agents and methods is contemplated.