The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Oct. 12, 2007
Jay Schneider, Coppell, TX (US);
Jenny Hsieh, Irving, TX (US);
Douglas Frantz, Flower Mound, TX (US);
Steven L. Mcknight, Dallas, TX (US);
Joseph M. Ready, Carrollton, TX (US);
Jay Schneider, Coppell, TX (US);
Jenny Hsieh, Irving, TX (US);
Douglas Frantz, Flower Mound, TX (US);
Steven L. McKnight, Dallas, TX (US);
Joseph M. Ready, Carrollton, TX (US);
The Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
The present invention relates to compounds and methods for inducing neuronal differentiation in normal neural stem cells and brain cancer stem cells. The compounds are isoxazole amides and derivatives thereof. The methods may take place in vitro, such as in isolates from the adult mammalian brain, or in vivo. Compounds and methods described herein may find use in the treatment of neurodegenerative and psychiatric diseases, the repair and regeneration of the nervous system, and in treatment of neurologic malignancy.