The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Nov. 11, 2009
Shuliang Zhang, Miami, FL (US);
Jiuliu LU, Homestead, FL (US);
Min Zheng, Pembroke Pines, FL (US);
Eric M. Grace, Cooper City, FL (US);
Jing LI, Miami, FL (US);
Maritza Lavernia, Miami, FL (US);
Ted W. Britton, Sunrise, FL (US);
Shuliang Zhang, Miami, FL (US);
Jiuliu Lu, Homestead, FL (US);
Min Zheng, Pembroke Pines, FL (US);
Eric M. Grace, Cooper City, FL (US);
Jing Li, Miami, FL (US);
Maritza Lavernia, Miami, FL (US);
Ted W. Britton, Sunrise, FL (US);
Beckman Coulter, Inc., Brea, CA (US);
Abstract
A method of correction of particle interference to hemoglobin measurement of a blood sample on a hematology analyzer is provided. The method includes mixing an aliquot of a blood sample with a lytic reagent to lyse red blood cells and forming a sample mixture; measuring absorbance of the sample mixture at a predetermined wavelength of a hemoglobin chromogen formed in the sample mixture, and obtaining an apparent hemoglobin concentration of the blood sample using obtained absorbance; measuring concentration and size of cellular particles remaining in the sample mixture; removing contribution of the cellular particles to the apparent hemoglobin concentration using the concentration and the size of the cellular particles to obtain a corrected hemoglobin concentration of the blood sample; and reporting the corrected hemoglobin concentration of the blood sample.