The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 05, 2012

Filed:

Apr. 07, 2005
Applicants:

Nana Jacobsen, Gentofte, DK;

Lars Kongsbak, Holte, DK;

Sakari Kauppinen, Smørum, DK;

Søren Morgenthaler Echwald, Humlebaek, DK;

Peter Mouritzen, Jyllinge, DK;

Peter Stein Nielsen, Birkerød, DK;

Mikkel Nørholm, København V, DK;

Inventors:

Nana Jacobsen, Gentofte, DK;

Lars Kongsbak, Holte, DK;

Sakari Kauppinen, Smørum, DK;

Søren Morgenthaler Echwald, Humlebaek, DK;

Peter Mouritzen, Jyllinge, DK;

Peter Stein Nielsen, Birkerød, DK;

Mikkel Nørholm, København V, DK;

Assignee:

Exiqon A/S, Vedbaek, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.


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