The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 05, 2012
Filed:
Jun. 01, 2006
Khalku Karim, Cambridge, GB;
Sergey Anatoliyovich Piletsky, Cranfield, GB;
Olena Volodimirivna Piletska, Cranfield, GB;
Anthony Peter Francis Turner, Wilstead, GB;
Iva Chianella, Silsoe, GB;
Antonio Ricardo Leonardo Guerriero, Cranfield, GB;
Khalku Karim, Cambridge, GB;
Sergey Anatoliyovich Piletsky, Cranfield, GB;
Olena Volodimirivna Piletska, Cranfield, GB;
Anthony Peter Francis Turner, Wilstead, GB;
Iva Chianella, Silsoe, GB;
Antonio Ricardo Leonardo Guerriero, Cranfield, GB;
Cranfield University, Bedfordshire, GB;
Abstract
The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.