The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Nov. 13, 2009
Marshall Donnie Graham, Nicholasville, KY (US);
William Gerry Graham, Nicholasville, KY (US);
James P. Clarkin, Scottsdale, AZ (US);
Mark A. Wells, Davie, FL (US);
Jose M. Cano, Miami, FL (US);
Carlos Alberto Arboleda, Miami, FL (US);
Armando Jose Sanchez, Miami, FL (US);
Marshall Donnie Graham, Nicholasville, KY (US);
William Gerry Graham, Nicholasville, KY (US);
James P. Clarkin, Scottsdale, AZ (US);
Mark A. Wells, Davie, FL (US);
Jose M. Cano, Miami, FL (US);
Carlos Alberto Arboleda, Miami, FL (US);
Armando Jose Sanchez, Miami, FL (US);
Beckman Coulter, Inc., Brea, CA (US);
Abstract
An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells). Manufactured from a monolithic transparent material, the improved flow cell has an internal flow channel of polygonal transverse cross-section through which prepared samples can be metered and an external envelope suited to acquisition of optical parameters from formed bodies in such samples. Preferably, such flow cell is formed by a glass-drawing process in which a relatively large glass preform having a rectilinear internal channel of a desired polygonal cross-sectional shape is heated and drawn to achieve a desired cross-sectional area of reduced size. Also disclosed are preferred methods for differentiating formed bodies using the flow cell of the invention.