The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Aug. 03, 2005
Tae Fukushima, Tokushima, JP;
Shuji Matsumura, Tokushima, JP;
Noriaki Takemura, Tokushima, JP;
Hideaki Satou, Tokushima, JP;
Nobuaki Ito, Tokushima, JP;
Takuya Shitsuta, Otsu, JP;
Hironori Tsutsui, Tokushima, JP;
Michinori Tanaka, Otsu, JP;
Keizo Kan, Tokushima, JP;
Hitoshi Nagao, Tokushima, JP;
Kenji Watanabe, Tokushima, JP;
Kuninori Tai, Tokushima, JP;
Takashi Nakagawa, Otsu, JP;
Hideki Takasu, Otsu, JP;
Makoto Sakamoto, Otsu, JP;
Keisuke Miyajima, Otsu, JP;
Satoshi Yamada, Otsu, JP;
Yutaka Kojima, Otsu, JP;
Koichi Yasumura, Otsu, JP;
Naoto Ohi, Otsu, JP;
Mitsuhiro Okuno, Otsu, JP;
Kazuhisa Sugiyama, Otsu, JP;
Kunihiko Kiyono, Otsu, JP;
Takashi Suzuki, Otsu, JP;
Seiji Akamatsu, Otsu, JP;
Takeshi Kodama, Otsu, JP;
Yasuo Yanagihara, Otsu, JP;
Takumi Sumida, Otsu, JP;
Tae Fukushima, Tokushima, JP;
Shuji Matsumura, Tokushima, JP;
Noriaki Takemura, Tokushima, JP;
Hideaki Satou, Tokushima, JP;
Nobuaki Ito, Tokushima, JP;
Takuya Shitsuta, Otsu, JP;
Hironori Tsutsui, Tokushima, JP;
Michinori Tanaka, Otsu, JP;
Keizo Kan, Tokushima, JP;
Hitoshi Nagao, Tokushima, JP;
Kenji Watanabe, Tokushima, JP;
Kuninori Tai, Tokushima, JP;
Takashi Nakagawa, Otsu, JP;
Hideki Takasu, Otsu, JP;
Makoto Sakamoto, Otsu, JP;
Keisuke Miyajima, Otsu, JP;
Satoshi Yamada, Otsu, JP;
Yutaka Kojima, Otsu, JP;
Koichi Yasumura, Otsu, JP;
Naoto Ohi, Otsu, JP;
Mitsuhiro Okuno, Otsu, JP;
Kazuhisa Sugiyama, Otsu, JP;
Kunihiko Kiyono, Otsu, JP;
Takashi Suzuki, Otsu, JP;
Seiji Akamatsu, Otsu, JP;
Takeshi Kodama, Otsu, JP;
Yasuo Yanagihara, Otsu, JP;
Takumi Sumida, Otsu, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein Xrepresents a nitrogen atom or a group —CH═; Rrepresents a group —Z—R, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and Rrepresents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; Rrepresents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein Rrepresents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and Rrepresents an imidazolyl lower alkyl group or the like.