The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Dec. 05, 2006
Hiroaki Suga, Tokyo, JP;
Hiroshi Murakami, Tokyo, JP;
Hiroaki Suga, Tokyo, JP;
Hiroshi Murakami, Tokyo, JP;
The University of Tokyo, Tokyo, JP;
Abstract
An object of the present invention is to provide novel ribozyme systems capable of catalyzing tRNA acetylation using various carboxylic acids as acyl donors and uses thereof. Disclosed is a ribozyme catalyzing tRNA acetylation having a structure consisting of the RNA sequence represented by: (formula 1) P1-ZZZZ(N)(N). . . (N)-P2-(N)(N). . . (N)YYY-(N)(N)-NGGwherein (N)-(N)each independently represent any monoribonucleotide of U, C, A, and G; p represents 3 or 4; (N)-(N)each independently represent any monoribonucleotide of U, C, A, and G; q represents 5 or 6; (N)-(N)each independently represent any monoribonucleotide of U, C, A, and G; Nrepresents any monoribonucleotide of U, C, A, and G; Z-Zeach independently represent C or G; Y-Yeach independently represent C or G;represents a monoribonucleotide complementary to A or G; and P1 and P2 represent a domain consisting of any RNA sequence capable of having a stem-loop structure.