The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Oct. 29, 2004
Eugen Uhlmann, Glashuetten, DE;
Jörg Vollmer, Duesseldorf, DE;
Arthur M. Krieg, Wellesley, MA (US);
Bernhard O. Noll, Neuss, DE;
Eugen Uhlmann, Glashuetten, DE;
Jörg Vollmer, Duesseldorf, DE;
Arthur M. Krieg, Wellesley, MA (US);
Bernhard O. Noll, Neuss, DE;
Coley Pharmaceutical GmbH, Dusseldorf, DE;
Coley Pharmaceutical Group, Inc., New York, NY (US);
Abstract
The invention relates to a class of CpG immunostimulatory oligonucleotides containing a CpG immunostimulatory motif and a second motif which is capable of forming secondary structure, including duplex and higher order structures, in vitro and in vivo. The oligonucleotides of the invention are useful as adjuvants in vaccination. The oligonucleotides are also useful for inducing an immune response, inducing expression of a type I interferon (IFN), inducing expression of gamma interferon (IFN-γ), and for treating a variety of conditions, including allergy, asthma, infection, and cancer.