The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2012

Filed:

Apr. 27, 2009
Applicants:

Michael G. Bramucci, Boothwyn, PA (US);

Andrew C. Eliot, Wilmington, DE (US);

Lori Ann Maggio-hall, Wilmington, DE (US);

Charles E. Nakamura, Claymont, DE (US);

Inventors:

Michael G. Bramucci, Boothwyn, PA (US);

Andrew C. Eliot, Wilmington, DE (US);

Lori Ann Maggio-Hall, Wilmington, DE (US);

Charles E. Nakamura, Claymont, DE (US);

Assignee:

Butamax(TM) Advanced Biofuels LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

From a bacterial strain isolated from an environmental sample, after enrichment in medium containing 1-butanol as the carbon source, a new enzyme with butanol dehydrogenase activity was identified. The enzyme can convert butyraldehyde to 1-butanol, isobutyraldehyde to isobutanol, as well as 2-butanone to 2-butanol and thus is useful for biosynthesis of butanol in recombinant microbial hosts producing these substrates. The encoding gene, named sadB, was isolated from the strain identified as an isolate of


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