The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
May. 08, 2009
Pirjo Laakkonen, Helsinki, FI;
Erkki Ruoslahti, La Jolla, CA (US);
Gabriele Bergers, San Francisco, CA (US);
Pirjo Laakkonen, Helsinki, FI;
Erkki Ruoslahti, La Jolla, CA (US);
Gabriele Bergers, San Francisco, CA (US);
Burnham Institute for Medical Research, La Jolla, CA (US);
The Regents of the University of California, UCSF, San Francisco, CA (US);
Abstract
The present invention relates to a peptide, which specifically homes to the intracranial, early stage astrocytoma model that grows as islets and harbors co-opted tumor vessels in the brain. The peptide finds its use in targeted delivery of therapeutic substances to invasive brain cancer or metastatic brain lesions as such and in combination with conventional therapies, such as surgery and radiation, and anti-angiogenic therapies, and as a tool in diagnosis of, e.g., invasive brain cancer or metastatic brain lesions.