The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 29, 2012

Filed:

Jan. 28, 2005
Applicants:

Samuel S. Murray, Saugus, CA (US);

Keyvan Behnam, Red Bank, NJ (US);

Elsa J. Brochmann-murray, Saugus, CA (US);

Inventors:

Samuel S. Murray, Saugus, CA (US);

Keyvan Behnam, Red Bank, NJ (US);

Elsa J. Brochmann-Murray, Saugus, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 4/12 (2006.01); C07K 5/12 (2006.01); C07K 14/51 (2006.01); C07K 14/495 (2006.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); A61K 38/18 (2006.01); A61F 2/26 (2006.01); A61P 19/00 (2006.01); C12N 5/07 (2010.01);
U.S. Cl.
CPC ...
Abstract

A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the over-all osteogenic activity of rgBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.


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