The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Oct. 26, 2006
Hyun Ah Kang, Daejeon, KR;
Jeong Seok Park, Chungcheongbuk-do, KR;
Moo Woong Kim, Daejeon, KR;
Eun Jung Kim, Daejeon, KR;
Hye Yun Moon, Daejeon, KR;
Doo Byoung OH, Daejeon, KR;
Joo Hyung Heo, Daejeon, KR;
Sang Ki Rhee, Seoul, KR;
Hyun Ah Kang, Daejeon, KR;
Jeong Seok Park, Chungcheongbuk-do, KR;
Moo Woong Kim, Daejeon, KR;
Eun Jung Kim, Daejeon, KR;
Hye Yun Moon, Daejeon, KR;
Doo Byoung Oh, Daejeon, KR;
Joo Hyung Heo, Daejeon, KR;
Sang Ki Rhee, Seoul, KR;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a process for producing a human-type glycoprotein having reduced glycosylation by genetically manipulating an enzyme involved in glycosylation using asystem. In detail, the present invention relates to a process for producing a human-type glycoprotein by identifying a dolichyl-phosphate-mannose dependent ¥á-1,3-mannosyltransferase gene from, constructing amutant strain producing a glycoprotein exhibiting reduced glycosylation by disrupting the identified gene, and subjecting the mutant strain to various genetic manipulations for the synthesis of human-type glycan.