The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
May. 08, 2007
Nabil G. Seidah, Ile Des Soeurs, CA;
Jean Davignon, Montrèal, CA;
Geneviève Dubuc, Longueuil, CA;
Lise Bernier, Montrèal, CA;
Michel Tremblay, Mascouche, CA;
Nabil G. Seidah, Ile Des Soeurs, CA;
Jean Davignon, Montrèal, CA;
Geneviève Dubuc, Longueuil, CA;
Lise Bernier, Montrèal, CA;
Michel Tremblay, Mascouche, CA;
Adaerata Limited Partnership, Montreal, CA;
Abstract
A chimera protein comprising in the following order: a signal peptide, a proprotein convertase subtilisin/kexin type 9 preproprotein (PCSK9) sequence consisting of amino acid residues at positions 35 to 696 of SEQ ID NO: 38, a transmembrane domain and a cytosolic domain, wherein said cytosolic (CT) domain comprises a sequence able to recycle the protein from the cellular membrane to endosomes.