The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
Jan. 08, 2010
David J. Ecker, Encinitas, CA (US);
Rangarajan Sampath, San Diego, CA (US);
Lawrence B. Blyn, Mission Viejo, CA (US);
Steven A. Hofstadler, Vista, CA (US);
Thomas A. Hall, Oceanside, CA (US);
David J. Ecker, Encinitas, CA (US);
Rangarajan Sampath, San Diego, CA (US);
Lawrence B. Blyn, Mission Viejo, CA (US);
Steven A. Hofstadler, Vista, CA (US);
Thomas A. Hall, Oceanside, CA (US);
Ibis Biosciences, Inc., Carlsbad, CA (US);
Abstract
The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon.