The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 29, 2012
Filed:
May. 29, 2009
Davinder S. Gill, Andover, MA (US);
Jing LI, Lexington, MA (US);
Geertruida M. Veldman, Sudbury, MA (US);
Lynette A. Fouser, Acton, MA (US);
Viia Valge-archer, Cambridge, GB;
David C. Lowe, Cambridge, GB;
Caroline S. Russell, Cambridge, GB;
Suzanne E. Cohen, Cambridge, GB;
Albert G. Thom, Cambridge, GB;
Ralph R. Minter, Cambridge, GB;
Davinder S. Gill, Andover, MA (US);
Jing Li, Lexington, MA (US);
Geertruida M. Veldman, Sudbury, MA (US);
Lynette A. Fouser, Acton, MA (US);
Viia Valge-Archer, Cambridge, GB;
David C. Lowe, Cambridge, GB;
Caroline S. Russell, Cambridge, GB;
Suzanne E. Cohen, Cambridge, GB;
Albert G. Thom, Cambridge, GB;
Ralph R. Minter, Cambridge, GB;
Wyeth LLC, Madison, NJ (US);
MedImmune Limited, Cambridge, GB;
Abstract
The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22). The antibodies can act as antagonists of IL-22 activity, thereby modulating immune responses in general, and those mediated by IL-22 in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.