The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2012

Filed:

Mar. 05, 2008
Applicants:

Paul Falkowski, Princeton, NJ (US);

Eric H. Andrianasolo, Kitchener, Ontario, CA;

Liti Haramaty, New Brunswick, NJ (US);

Eileen White, Princeton, NJ (US);

Richard Lutz, New Brunswick, NJ (US);

Inventors:

Paul Falkowski, Princeton, NJ (US);

Eric H. Andrianasolo, Kitchener, Ontario, CA;

Liti Haramaty, New Brunswick, NJ (US);

Eileen White, Princeton, NJ (US);

Richard Lutz, New Brunswick, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 407/06 (2006.01); C07C 69/74 (2006.01); C07C 69/035 (2006.01); A61K 31/352 (2006.01); A61K 31/215 (2006.01); A61K 31/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formulas I-IV: (I), (II), (III) (IV), wherein: Rand R-Rare independently selected from H and 1-3 carbon lower alkyl; and Rand Rare independently selected from H, 1-3 carbon lower O II alkyl, and —C—R, wherein Ris 1-3 carbon lower alkyl. Pharmaceutical compositions, which include any of Compounds I-IV and a pharmaceutically acceptable carrier, methods of inducing tumor cell apoptosis by administering to a patient in need thereof an effective amount of any of Compounds I-IV, and methods for obtaining any of Compounds I-IV by extracting the compound from coral are also provided.


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