The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8183383 B1

PDF
Full Text
Expired
Date of Patent:
May. 22, 2012

Filed:

Feb. 26, 2008
Applicants:

Fajun Nan, Shanghai, CN;

Jia LI, Shanghai, CN;

Yi Wei, Shanghai, CN;

Wei Zhang, Shanghai, CN;

Jingya LI, Shanghai, CN;

Lei Shi, Shanghai, CN;

Inventors:

Fajun Nan, Shanghai, CN;

Jia Li, Shanghai, CN;

Yi Wei, Shanghai, CN;

Wei Zhang, Shanghai, CN;

Jingya Li, Shanghai, CN;

Lei Shi, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 277/30 (2006.01); C07D 263/34 (2006.01); C07D 233/00 (2006.01); C07D 233/61 (2006.01); C07D 417/10 (2006.01); C07D 413/10 (2006.01); C07D 401/10 (2006.01); A61K 31/445 (2006.01); A61K 31/44 (2006.01); A61K 31/425 (2006.01); A61K 31/42 (2006.01); A61K 31/415 (2006.01);
U.S. Cl.
CPC ...
Abstract

PTP1B inhibitors with the following structure (formula I). Experiments indicate that these inhibitors can effectively inhibit the activity of protein tyrosine phosphatase 1B (PTP1B). They can be used as insulin sensitisers. They can be used to prevent, delay or treat diseases which are related to insulin antagonism mediated by PTP1B, especially diabetes type II and obesity. The invention also provides methods for preparing these inhibitors.


Find Patent Forward Citations

Nan, Fajun. (2012). Protein tyrosine phosphatase 1b inhibitor, preparation methods and uses thereof (U.S. Patent No. 8183383). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8183383

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