The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2012

Filed:

Nov. 14, 2008
Applicants:

Jerome P. Horwitz, Farmington Hills, MI (US);

Lisa Polin, Oak Park, MI (US);

Stuart T. Hazeldine, Taylor, MI (US);

Thomas H. Corbett, Grosse Pointe Park, MI (US);

Inventors:

Jerome P. Horwitz, Farmington Hills, MI (US);

Lisa Polin, Oak Park, MI (US);

Stuart T. Hazeldine, Taylor, MI (US);

Thomas H. Corbett, Grosse Pointe Park, MI (US);

Assignee:

Wayne State University, Detroit, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/227 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds of formula I: wherein Y is F or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof, and methods of inhibiting cancer cells.


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