The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Dec. 01, 2009
Donmienne Doen Mun Leung, San Diego, CA (US);
Peng Luan, Livermore, CA (US);
Joseph Vincent Manetta, Indianapolis, IN (US);
Ying Tang, San Diego, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Donmienne Doen Mun Leung, San Diego, CA (US);
Peng Luan, Livermore, CA (US);
Joseph Vincent Manetta, Indianapolis, IN (US);
Ying Tang, San Diego, CA (US);
Derrick Ryan Witcher, Fishers, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.