The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2012

Filed:

Dec. 18, 2008
Applicants:

Mark Grillo, San Francisco, CA (US);

An-rong LI, San Mateo, CA (US);

Jiwen Liu, Foster City, CA (US);

Julio C. Medina, San Carlos, CA (US);

Yongli Su, Foster City, CA (US);

Yingcai Wang, Millbrae, CA (US);

Janan Jona, Simi Valley, CA (US);

Alan Allgeier, Oak Park, CA (US);

Jacqueline Milne, Simi Valley, CA (US);

Jerry Murry, Newbury Park, CA (US);

Joseph F. Payack, Somerset, NJ (US);

Thomas Storz, Warwick, NY (US);

Inventors:

Mark Grillo, San Francisco, CA (US);

An-Rong Li, San Mateo, CA (US);

Jiwen Liu, Foster City, CA (US);

Julio C. Medina, San Carlos, CA (US);

Yongli Su, Foster City, CA (US);

Yingcai Wang, Millbrae, CA (US);

Janan Jona, Simi Valley, CA (US);

Alan Allgeier, Oak Park, CA (US);

Jacqueline Milne, Simi Valley, CA (US);

Jerry Murry, Newbury Park, CA (US);

Joseph F. Payack, Somerset, NJ (US);

Thomas Storz, Warwick, NY (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/18 (2006.01); C07C 311/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives.


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