The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 22, 2012

Filed:

Nov. 22, 2007
Applicants:

Didier Roche, Saclay, FR;

Denis Carniato, Marcoussis, FR;

Liliane Doare, Vitry-Chatillon, FR;

Christine Charon, Gometz-le-Chatel, FR;

Caroline Leriche, Paris, FR;

Inventors:

Didier Roche, Saclay, FR;

Denis Carniato, Marcoussis, FR;

Liliane Doare, Vitry-Chatillon, FR;

Christine Charon, Gometz-le-Chatel, FR;

Caroline Leriche, Paris, FR;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/80 (2006.01); A01N 43/40 (2006.01); A61K 31/42 (2006.01); A61K 31/44 (2006.01); C07D 261/00 (2006.01); C07D 413/00 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to 2-adamantyl-butyramide derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.


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