The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
May. 10, 2006
Advait Nagle, San Diego, CA (US);
Nathanael Schiander Gray, Boston, MA (US);
Yi Liu, San Diego, CA (US);
Pingda Ren, San Diego, CA (US);
Taebo Sim, San Diego, CA (US);
Shuli You, Shanghai, CN;
Advait Nagle, San Diego, CA (US);
Nathanael Schiander Gray, Boston, MA (US);
Yi Liu, San Diego, CA (US);
Pingda Ren, San Diego, CA (US);
Taebo Sim, San Diego, CA (US);
Shuli You, Shanghai, CN;
IRM LLC, Hamilton, BM;
Abstract
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of Abl, Bcr-Abl, Bmx, BTK, b-RAF, c RAF, CSK, cSRC, Fes, FGFR3, Flt3, IKKα, IKKβ, JNK1α1, JNK2α2, Lck, Met, MKK4, MKK6, p70S6K, PAK2, PDGFRα, PKA, PKCα, PKD2, ROCK-II, Ros, Rsk1, SAPK2α, SAPK2β, SAPK3, SAPK4, SGK, Syk, Tie2 and TrkB kinases.