The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Oct. 13, 2009
Jixing Liu, Lanzhou, CN;
Bin Yang, Lanzhou, CN;
Xi Lan, Lanzhou, CN;
Xiangping Yin, Lanzhou, CN;
Yinmei Bai, Lanzhou, CN;
Xiaorong Han, Lanzhou, CN;
Xuerui LI, Lanzhou, CN;
Baoyu LI, Lanzhou, CN;
Yuping Fang, Lanzhou, CN;
Zhiyong LI, Lanzhou, CN;
Jixing Liu, Lanzhou, CN;
Bin Yang, Lanzhou, CN;
Xi Lan, Lanzhou, CN;
Xiangping Yin, Lanzhou, CN;
Yinmei Bai, Lanzhou, CN;
Xiaorong Han, Lanzhou, CN;
Xuerui Li, Lanzhou, CN;
Baoyu Li, Lanzhou, CN;
Yuping Fang, Lanzhou, CN;
Zhiyong Li, Lanzhou, CN;
Abstract
A double-effective vaccine vector against foot-and-mouth disease virus having a bicistronic expression vector sequence, the bicistronic expression vector sequence is an antisense gene sequence capable of conjugating with 5' UTR of RNA of the foot-and-mouth disease virus genome and an intact sequence of VP1 structural protein gene of the foot-and-mouth disease virus. Animal experiments show that the vaccine vector provides double effects in terms of gene therapy and gene immunization for the prevention and treatment of foot-and-mouth disease in animals. Also provided are construction methods and methods of use of the vaccine vector.