The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Feb. 25, 2011
Woei-jer Chuang, Tainan, TW;
Wen-mei Fu, Taipei, TW;
Mannching Sherry Ku, Thiells, NY (US);
Yen-lun Huang, Taoyuan County, TW;
Woei-Jer Chuang, Tainan, TW;
Wen-Mei Fu, Taipei, TW;
Mannching Sherry Ku, Thiells, NY (US);
Yen-Lun Huang, Taoyuan County, TW;
National Cheng Kung University, Tainan, TW;
National Taiwan University, Taipei, TW;
Abstract
The invention provides disintegrin variants, and more specifically to disintegrin variants which are selective αvβ3 integrin antagonists for treatment and prevention of αvβ3 integrin-associated diseases. The present invention also relates to pegylated proteins, including proteins comprising a disintegrin variant having an RGD motif variantARLDDL. The invention also relates to the use of the polypeptides of the invention for the treatment and prevention of αvβ3 integrin-associated diseases.