The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Sep. 29, 2006
Jun-ichi Tanabe, Kanagawa, JP;
Saburo Sone, Kanagawa, JP;
Takaji Wakita, Tokyo, JP;
Koji Ishii, Tokyo, JP;
Ryosuke Suzuki, Chiba, JP;
Tetsuro Suzuki, Tokyo, JP;
Tatsuo Miyamura, Tokyo, JP;
Jun-ichi Tanabe, Kanagawa, JP;
Saburo Sone, Kanagawa, JP;
Takaji Wakita, Tokyo, JP;
Koji Ishii, Tokyo, JP;
Ryosuke Suzuki, Chiba, JP;
Tetsuro Suzuki, Tokyo, JP;
Tatsuo Miyamura, Tokyo, JP;
Abstract
The present invention relates to a method for producing a recombinant hepatitis C virus-like particle comprising the steps of introducing into (i) a cell in which an RNA replicon comprising a nucleotide sequence comprising the 5' untranslated region, the nucleotide sequence coding for the NS3, NS4A, NS4B, NS5A, and NS5B proteins, and the 3′ untranslated region of a genome RNA derived from a hepatitis C virus strain autonomously replicates, (ii) a vector expressing the Core, E1, E2, and p7 proteins derived from a hepatitis C virus strain that is the same as or different from that as defined in the above (i), culturing the cell, and recovering the produced virus-like particle, and a recombinant hepatitis C virus particle produced by this method.