The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 22, 2012
Filed:
Jun. 03, 2005
Applicants:
Dirk Henning Lenz, Wellington, NZ;
Jennifer Mary Mason, Wellington, NZ;
Keith Clinch, Wellington, NZ;
Gary Brian Evans, Wellington, NZ;
Peter Charles Tyler, Wellington, NZ;
Inventors:
Dirk Henning Lenz, Wellington, NZ;
Jennifer Mary Mason, Wellington, NZ;
Keith Clinch, Wellington, NZ;
Gary Brian Evans, Wellington, NZ;
Peter Charles Tyler, Wellington, NZ;
Assignee:
Industrial Research Limited, Lower Hutt, NZ;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/10 (2006.01); C07D 295/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process is disclosed for preparing (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (I), or (3S,4S)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (Ia) involving, as a key step, the enzyme-catalysed enantioselective hydrolysis of a racemic 3,4-trans-disubstituted pyrrolidinone compound of formula (II).